It's 1959 and Harry Rabbit' Angstrom, one time high school sports superstar, is going nowhere. At twenty-six, he is trapped in a second-rate existence - stuck with a fragile, alcoholic wife, a house full of overflowing ashtrays and discarded glasses, a young son and a futile job. With no way to fix things, he resolves to flee from his family and his home in Pennsylvania, beginning a thousand-mile journey that he hopes will free him from his mediocre life. Because, as he knows only too well, after you've been first-rate at something, no matter what, it kind of takes the kick out of being second-rate'.

The air of Eastwick breeds witches - women whose powerful longings can stir up thunderstorms and fracture domestic peace. Jane, Alexandra and Sukie, divorced and dangerous, have formed a coven. Into the void of Eastwick breezes Darryl Van Horne, a charismatic magus of a man who entrances the trio, luring them to his mansions...